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Experts from the National Amyloidosis Centre in London examine three case studies, specifically focusing upon the symptoms that first aroused suspicion, the diagnostic tests that confirmed the condition, and the treatment options available to these patients.

AstraZeneca has provided a sponsorship towards this independent programme. AstraZeneca has had no editorial input into or control over the agenda, content development or choice of speakers, nor opportunity to influence.

A guide for all members of the cardiovascular and primary care teams on what to look for, and what to do if you suspect amyloidosis: signs and symptoms, diagnostic tests and studies, and the treatment options currently available.

Funding for this video has come from multiple pharmaceutical industry sponsors. Further details of each company’s involvement can be found on the video page.

Sponsored

Dr Rajiv Sankaranarayanan, Consultant Cardiologist, University Hospitals Liverpool is joined by Dr Parin Shah, Consultant Cardiologist, Swansea Bay University Health Board and Matthew Sunter, Lead Heart Failure Nurse, St. George's University Hospital, London as they share how they’ve implemented and adapted the STRONG-HF1 pathway to improve heart failure care. They discuss early patient identification, rapid optimisation, and collaborative follow-up models tailored to local needs. Through shared learning and teamwork across disciplines, each centre has refined its approach to deliver more efficient, patient-centred heart failure management.

MC-UK-01533 | December 2025

This Masterclass was developed in collaboration with the National Amyloidosis Centre, London UK

Assessment of a patient with suspected amyloidosis requires a careful diagnostic workup, including cardiac imaging to identify amyloid infiltration in heart tissue that could lead to diastolic dysfunction and heart failure. In this Masterclass, clinicians and scientists from the National Amyloidosis Centre describe the laboratory tests and imaging techniques used to make an accurate diagnosis.
This Masterclass was developed in collaboration with the National Amyloidosis Centre, London UK

Effective treatment of cardiac amyloidosis is dependent on early diagnosis; it is therefore important that clinicians have a high index of suspicion for the condition in their patients. Dr Josephine Mansell from the National Amyloidosis Centre outlines the “red flag” signs and symptoms that cardiologists, nurses or other healthcare professionals may observe in their patients, and which should prompt consideration of referral for a full diagnostic workup.
 

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